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Topicals to Control & Kill Dog Fleas and Ticks

Flea and tick treatment for dogs, cats, and pets here provide relief with topical application. Units are are available for monthly to yearly supplies from brands including Pronyl, Frontline, Revolution, Advantage, and more.

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NexGard Flea and Tick Chewables for Dogs - Jeffers - Animal Health & Wellness > Flea & Tick Control
NexGard Flea and Tick Chewables for Dogs - Jeffers - Animal Health & Wellness > Flea & Tick Control Save up to 7% Save %
$35.99 - $170.99
$35.99 - $170.99
$35.99
$32.89 - $159.99
$32.89 - $159.99
$32.89

NexGard Flea and Tick Chewables for Dogs

NexGard
Out of stock

NexGard™ Chewables A convenient solution to an annoying problem—NexGard is the first flea and tick killer in a beef-flavored chew, a piece of he...

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Frontline Gold for Dogs - Jeffers - Animal Health & Wellness > Flea & Tick Control
Frontline Gold for Dogs - Jeffers - Animal Health & Wellness > Flea & Tick Control Save up to 13% Save %
$19.33 - $108.99
$19.33 - $108.99
$19.33
$12.95 - $94.99
$12.95 - $94.99
$12.95

Frontline Gold for Dogs

Frontline
Out of stock

Frontline Gold for Dogs Frontline Gold is a once-a-month topical treatment with a new triple action formula that combines two *IGR's to destroy fle...

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Orm-d Vet-Kem Flea Tick & Bot Spray 16 ounce bottle - 16 oz Sold out
$14.99 - $14.99
$14.99
$14.99
$14.99 - $14.99
$14.99

Vet-Kem Flea, Tick & Bot Spray, 16 oz

PRN Pharmacal
Out of stock

Vet-Kem Flea, Tick & Bot Spray For use on dogs, cats and horses, Vet-Kem Flea, Tick & Bot Spray kills and repels fleas, ticks, lice, flies,...

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Best Shot All Natural Bug Spray - Jeffers - Animal Health & Wellness > Flea & Tick Control
Best Shot All Natural Bug Spray - Jeffers - Animal Health & Wellness > Flea & Tick Control Save up to 45% Save %
$20.99 - $76.99
$20.99 - $76.99
$20.99
$11.95 - $42.00
$11.95 - $42.00
$11.95

Best Shot All Natural Bug Spray

Best Shot Pet
Out of stock

All Natural Bug Spray by Best Shot Pet A proven remedy for an age old problem! Natural Bug Spray features safe, non-sticky organic extracts that wo...

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Frontline Plus for Dogs - Jeffers - Animal Health & Wellness > Flea & Tick Control
Frontline Plus for Dogs - Jeffers - Animal Health & Wellness > Flea & Tick Control
Save up to 17% Save %
$51.99 - $85.99
$51.99 - $85.99
$51.99
$42.98 - $78.99
$42.98 - $78.99
$42.98

Frontline Plus for Dogs

Merial
Out of stock

Frontline Plus for Dogs Once-a-month, topical spot-on treatments for fast-acting, long-lasting control of fleas, ticks, flea eggs, and lice. Frontl...

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TevraPet Activate II, 4 Month Supply - Jeffers - Animal Health & Wellness > Flea & Tick Control
TevraPet Activate II, 4 Month Supply - Jeffers - Animal Health & Wellness > Flea & Tick Control
Save 10% Save %
$29.99
$29.99 - $29.99
$29.99
$26.97
$26.97 - $26.97
$26.97

TevraPet Activate II, 4 Month Supply

Activate II
Out of stock

TevraPet Activate II, 4 Month Supply TevraPet Activate II provides a 4-month supply of effective, vet-quality flea and tick control for dogs. With ...

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Vetality Avantect II Flea & Tick Topical for Dogs, 4 - pack - Jeffers - Animal Health & Wellness > Flea & Tick Control
Vetality Avantect II Flea & Tick Topical for Dogs, 4 - pack - Jeffers - Animal Health & Wellness > Flea & Tick Control
Save 25% Save %
$39.96
$39.96 - $39.96
$39.96
$29.97
$29.97 - $29.97
$29.97

Vetality Avantect II Flea & Tick Topical for Dogs, 4 pk

Tevra Brands
Out of stock

Avantect II Flea & Tick Topical for Dogs Avantect II for dogs contains the same 3 active ingredients as K9 Advantix by Bayer. The waterproof fo...

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Vetality Firstect Plus for Dogs, 3 - pack - Jeffers - Animal Health & Wellness > Flea & Tick Control
Vetality Firstect Plus for Dogs, 3 - pack - Jeffers - Animal Health & Wellness > Flea & Tick Control
Save 25% Save %
$27.49
$27.49 - $27.49
$27.49
$20.62
$20.62 - $20.62
$20.62

Vetality Firstect Plus for Dogs, 3-pack

Tevra Brands
Out of stock

Vetality Firstect Plus for DogsFirstect Plus contains the same active ingredients as Frontline Plus for Dogs. Fast-acting and long-lasting Firstect...

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Frontline Gold 5 - 22 lbs, Single - Jeffers - Animal Health & Wellness > Flea & Tick Control
Frontline Gold 5 - 22 lbs, Single - Jeffers - Animal Health & Wellness > Flea & Tick Control
Sold out
$19.33
$19.33 - $19.33
$19.33
$18.33
$18.33 - $18.33
$18.33

Frontline Gold 5-22 lbs, Single

Frontline
Out of stock

Frontline Gold Flea & Tick Treatment for Dogs, 5-22 lbs, Single Protect your small dog with the powerful, triple-action formula of Frontline...

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Certifect for Dogs - Jeffers - Animal Health & Wellness > Flea & Tick Control
Certifect for Dogs - Jeffers - Animal Health & Wellness > Flea & Tick Control
Sold out
$12.99 - $37.99
$12.99
$12.99 - $37.99
$12.99 - $37.99
$12.99

Certifect Flea & Tick for Dogs

Certifect
Out of stock

Certifect Flea & Tick for Dogs Stop ticks, fleas, and chewing lice dead in their tracks with Certifect for Dogs, a topical treatment that works...

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Espree Flea & Tick Spray - Jeffers - Animal Health & Wellness > Flea & Tick Control
Espree Flea & Tick Spray - Jeffers - Animal Health & Wellness > Flea & Tick Control
Sold out
$11.29 - $11.29
$11.29
$11.99
$11.99 - $11.99
$11.99

Espree Flea & Tick Spray

Espree
Out of stock

Espree Flea & Tick SprayUse this convenient Espree Flea & Tick Spray to kill fleas, ticks and lice on your dog. Starts killing on contact a...

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Martin's Flee RTU Yard Spray - Jeffers - Animal & Pet Supplies > Pet Containment Systems
Sold out
$17.99 - $17.99
$17.99
$17.99
$17.99 - $17.99
$17.99

Martin's Flee RTU Yard Spray

Martin's
Out of stock

Martin's Flee RTU Yard Spray Martin's Flee RTU Yard Spray is a ready-to-spray insecticide that kills insect pests that infest your lawn and orna...

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Advantage Household Fogger, 3 pack - Jeffers - Animal Health & Wellness > Flea & Tick Control
Advantage Household Fogger, 3 pack - Jeffers - Animal Health & Wellness > Flea & Tick Control
Sold out
$21.98 - $21.98
$21.98
$21.98
$21.98 - $21.98
$21.98

Advantage Household Fogger, 3 pack

Elanco
Out of stock

Advantage Household Fogger, 3 pack Advantage® Household Fogger reaches fleas and other listed insects hidden in places you can’t see, such as ca...

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DeFlea Shampoo for Pets, Ready to Use - Jeffers - Animal Health & Wellness > Flea & Tick Control
DeFlea Shampoo for Pets, Ready to Use - Jeffers - Animal Health & Wellness > Flea & Tick Control
Sold out
$13.49 - $17.99
$13.49 - $17.99
$13.49
$9.49 - $15.29
$9.49 - $15.29
$9.49

DeFlea Shampoo for Pets, Ready to Use

Natural Chemistry
Out of stock

DeFlea Shampoo for Dogs DeFlea Shampoo for Dogs contains Dioctyl Sodium Sulfosuccinate (a common food additive) and Undeclyenic Acid (a derivative ...

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Natural Flea & Tick Spray, 24 oz - Jeffers - Animal Health & Wellness > Flea & Tick Control
Natural Flea & Tick Spray, 24 oz - Jeffers - Animal Health & Wellness > Flea & Tick Control
Sold out
$16.49
$16.49 - $16.49
$16.49
$13.99
$13.99 - $13.99
$13.99

Natural Flea & Tick Spray, 24 oz

Natural Chemistry
Out of stock

Natural Flea & Tick Spray Natural's Chemistry Natural Formula is composed of natural cinnamon oil, clove oil, and cedar wood oil which kills...

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Midamox for Dogs - Jeffers - Animal Health & Wellness > Flea & Tick Control
Midamox for Dogs - Jeffers - Animal Health & Wellness > Flea & Tick Control
Sold out
$73.00 - $73.00
$73.00
$74.99
$74.99 - $74.99
$74.99

Midamox (imidacloprid + moxidectin) Once-A-Month Topical Solution for Dogs, 6 Pack

Midamox
Out of stock

Midamox for Dogs Meet Midamox (imidacloprid + moxidectin) topical solution from Norbrook, an affordable alternative to Advantage Multi. Made with t...

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Bronco e Equine Fly Spray - Jeffers - Animal Health & Wellness > Fly & Insect Control
Bronco e Equine Fly Spray - Jeffers - Animal Health & Wellness > Fly & Insect Control
Save up to 11% Save %
$11.99 - $31.49
$11.99 - $31.49
$11.99
$10.99 - $27.99
$10.99 - $27.99
$10.99

Bronco e Equine Fly Spray

Farnam
Out of stock

Bronco e Equine Fly Spray Contains 0.033% Prallethrins and 0.5% Piperonyl Butoxide and 0.1% Permethrin to control house, horse, horn, stable a...

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Flys - Off® Insect Repellent Spray, 6 oz - Jeffers - Animal Health & Wellness > Flea & Tick Control
Flys - Off® Insect Repellent Spray, 6 oz - Jeffers - Animal Health & Wellness > Flea & Tick Control
Sold out
$8.99
$8.99 - $8.99
$8.99
$7.64
$7.64 - $7.64
$7.64

Flys-Off® Insect Repellent Spray, 6 oz

Farnam
Out of stock

Flys-Off® Insect Repellent SprayFlys-Off® Insect Repellent Spray is effective in killing fleas, lice, and ticks. It temporarily repels flies, gnats...

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Adams Flea & Tick Cleansing Shampoo - Jeffers - Animal Health & Wellness > Flea & Tick Control
Adams Flea & Tick Cleansing Shampoo - Jeffers - Animal Health & Wellness > Flea & Tick Control
Sold out
$13.99 - $13.99
$13.99
$14.98
$14.98 - $14.98
$14.98

Adams Flea & Tick Cleansing Shampoo

Adams
Out of stock

Adams Flea & Tick Cleansing Shampoo Contains Pyrethrins, Piperonyl Butoxid, & Pyriproxyfen for quick kill of fleas, lice and ticks on do...

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Espree Flea & Tick Repellent Wipes - Jeffers - Animal Health & Wellness > Flea & Tick Control
Espree Flea & Tick Repellent Wipes - Jeffers - Animal Health & Wellness > Flea & Tick Control
Sold out
$0.00 - $0.00
$0.00
$11.99
$11.99 - $11.99
$11.99

Espree Flea & Tick Repellent Wipes

Espree
Out of stock

Espree Flea & Tick Wipes Stop biting and irritation caused by fleas and ticks. Espree Flea & Tick Wipes contain natural herbal oils to s...

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Adventure Plus for Dogs, 4 - Pack - Jeffers - Animal Health & Wellness > Flea & Tick Control
Adventure Plus for Dogs, 4 - Pack - Jeffers - Animal Health & Wellness > Flea & Tick Control
Sold out
$29.99
$29.99 - $29.99
$29.99
$27.99
$27.99 - $27.99
$27.99

Adventure Plus for Dogs, 4 pk

Manna Pro Corporation
Out of stock

Adventure Plus Topical Flea Treatment Adventure Plus Topical Flea Treatment provides fast and effective protection against fleas and lice. Formulat...

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Pyranha Pyrethrin Shampoo - Jeffers - Animal Health & Wellness > Flea & Tick Control
Pyranha Pyrethrin Shampoo - Jeffers - Animal Health & Wellness > Flea & Tick Control
Sold out
$13.99 - $13.99
$13.99
$13.99
$13.99 - $13.99
$13.99

Pyranha Pyrethrin Shampoo

Pyranha
Out of stock

Pyranha® Pyrethrin Shampoo for horses and dogs The Pyranha® Pyrethrin Flea & Tick Insecticidal Shampoo is rich in coconut conditioners that aid...

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ZoGuard Plus for Dogs, 3 pack - Jeffers - Animal Health & Wellness > Flea & Tick Control
ZoGuard Plus for Dogs, 3 pack - Jeffers - Animal Health & Wellness > Flea & Tick Control
$0.00 - $21.99
$0.00
$26.99
$26.99 - $26.99
$26.99

ZoGuard Plus for Dogs, 3 pack

ZoGuard
Out of stock

ZoGuard Plus for Dogs (3-Month Supply) A once-a-month flea & tick treatment that helps combat fleas, ticks, lice, and mites. Made with the sam...

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Permectrin II Insecticide - Jeffers - Farm & Ranch Supplies > Pest Control
Permectrin II Insecticide - Jeffers - Farm & Ranch Supplies > Pest Control
Save up to 20% Save %
$14.99 - $28.99
$14.99 - $28.99
$14.99
$11.99 - $27.99
$11.99 - $27.99
$11.99

Permectrin II Insecticide

Bayer
Out of stock

Permectrin II Insecticide Contains 10% Permethrin. For use on horses, beef and dairy cattle, swine, sheep, poultry, dogs and their premises. Per...

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Salvo Flea & Tick Collars for Dogs - Jeffers - Animal Health & Wellness > Flea & Tick Control
Salvo Flea & Tick Collars for Dogs - Jeffers - Animal Health & Wellness > Flea & Tick Control
Save up to 17% Save %
$29.41 - $31.49
$29.41 - $31.49
$29.41
$25.99
$25.99 - $25.99
$25.99

Salvo Flea & Tick Collars for Dogs

Manna Pro Corporation
Out of stock

Salvo Flea and Tick Collars Apply one Salvo collar every 6 months for continuous flea and tick protection.Salvo Collars Key Features: fast actin...

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Martin's Flee Plus IGR for Dogs - Jeffers - Animal Health & Wellness > Flea & Tick Control
Martin's Flee Plus IGR for Dogs - Jeffers - Animal Health & Wellness > Flea & Tick Control
Sold out
$19.99
$19.99 - $19.99
$19.99
$14.61 - $19.99
$14.61 - $19.99
$14.61

Martin's Flee Plus IGR for Dogs

Martin's
Out of stock

Martin's Flee Plus IGR for DogsCompare to FRONTLINE Plus for DogsMartin's Flee Plus IGR for Dogs contains fipronil and (S)-methoprene (insect growt...

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Spectra Shield Collar Medallion for Dogs - Jeffers - Animal Health & Wellness > Flea & Tick Control
Spectra Shield Collar Medallion for Dogs - Jeffers - Animal Health & Wellness > Flea & Tick Control
Save 11% Save %
$17.99
$17.99 - $17.99
$17.99
$15.99
$15.99 - $15.99
$15.99

Spectra Shield Collar Medallion for Dogs

Durvet Inc
Out of stock

Spectra Shield™ Dog Flea & Tick Medallions Just clip and go! No mess, no stress. Offers up to 4 months protection from fleas and ticks! Contai...

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Frontline Gold for Dogs, 6 - pack - Jeffers - Animal Health & Wellness > Flea & Tick Control
Frontline Gold for Dogs, 6 - pack - Jeffers - Animal Health & Wellness > Flea & Tick Control
$94.99 - $94.99
$94.99
$94.99
$94.99 - $94.99
$94.99

Frontline Gold for Dogs, 6-pack

Frontline
Out of stock

Frontline Gold, 6-pack Frontline Gold is a once-a-month topical treatment with a new triple action formula that combines two *IGR's to destroy f...

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K9 Advantix II Flea and Tick Prevention for Dogs - Jeffers - Animal Health & Wellness > Flea & Tick Control
K9 Advantix II Flea and Tick Prevention for Dogs - Jeffers - Animal Health & Wellness > Flea & Tick Control
Save up to 11% Save %
$35.68 - $89.99
$35.68 - $89.99
$35.68
$35.68 - $79.98
$35.68 - $79.98
$35.68

K9 Advantix II Flea and Tick Prevention for Dogs

Elanco
Out of stock

K9 Advantix II for Dogs A broad spectrum protection that not only kills but repels fleas, ticks, and mosquitoes, this convenient once a once-a-mont...

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TevraPet FirstAct Plus for Dogs, 3 Month Supply - Jeffers - Animal Health & Wellness > Flea & Tick Control
TevraPet FirstAct Plus for Dogs, 3 Month Supply - Jeffers - Animal Health & Wellness > Flea & Tick Control
Save 0% Save %
$19.99
$19.99 - $19.99
$19.99
$19.97
$19.97 - $19.97
$19.97

TevraPet FirstAct Plus for Dogs, 3 Month Supply

FirstAct Plus
Out of stock

TevraPet FirstAct Plus for Dogs, 3 Month Supply Prevent your pupper from turning pests into house guests with TevraPet FirstAct Plus Flea & Tic...

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Advantage II for Dogs - Jeffers - Animal Health & Wellness > Flea & Tick Control
Advantage II for Dogs - Jeffers - Animal Health & Wellness > Flea & Tick Control
Save up to 15% Save %
$59.99 - $69.99
$59.99 - $69.99
$59.99
$50.98 - $66.98
$50.98 - $66.98
$50.98

Advantage II for Dogs

Elanco
Out of stock

Elanco Advantage II for Dogs Advantage II for dogs controls existing flea infestations on your dog and prevents further infestations from occurr...

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Vetality Avantect II Flea & Tick Collar for Dogs, 2 pack - Jeffers - Animal Health & Wellness > Flea & Tick Control
Vetality Avantect II Flea & Tick Collar for Dogs, 2 pack - Jeffers - Animal Health & Wellness > Flea & Tick Control
Save 25% Save %
$39.96
$39.96 - $39.96
$39.96
$29.97
$29.97 - $29.97
$29.97

Vetality Avantect II Flea & Tick Collar for Dogs, 2 pack

Vetality
Out of stock

Vetality Avantect II Flea & Tick Collar for Dogs, 2 pack Vetality Avantect II Collar for dogs provides your dog with high-quality flea and t...

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ZoGuard Plus for Dogs, 6 pack - Jeffers - Animal Health & Wellness > Flea & Tick Control
ZoGuard Plus for Dogs, 6 pack - Jeffers - Animal Health & Wellness > Flea & Tick Control
Sold out
$46.99
$46.99 - $46.99
$46.99
$29.99
$29.99 - $29.99
$29.99

ZoGuard Plus for Dogs, 6 pack

ZoGuard
Out of stock

ZoGuard Plus for Dogs, 6 pack One of the only products containing the same flea and tick fighting protection as Frontline Plus.ZoGuard Plus 3Key B...

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FiproGuard for Dogs - Jeffers - Animal Health & Wellness > Flea & Tick Control
FiproGuard for Dogs - Jeffers - Animal Health & Wellness > Flea & Tick Control
Save up to 45% Save %
$19.80 - $32.99
$19.80 - $32.99
$19.80
$17.99 - $27.99
$17.99 - $27.99
$17.99

FiproGuard for Dogs

Sentry
Out of stock

FiproGuard™ for Dogs For dogs over 8 weeks of age. FiproGuard™ contains Fipronil, the same active ingredient used in Frontline® Top Spot® for dogs....

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SENTRY Fiproguard Plus for Dogs, 3 Pack - Jeffers - Animal Health & Wellness > Flea & Tick Control
SENTRY Fiproguard Plus for Dogs, 3 Pack - Jeffers - Animal Health & Wellness > Flea & Tick Control
Save 10% Save %
$24.99
$24.99 - $24.99
$24.99
$22.49
$22.49 - $22.49
$22.49

SENTRY Fiproguard Plus for Dogs, 3 Pack

Sentry
Out of stock

SENTRY Fiproguard Plus New SENTRY Fiproguard Plus has the same active ingredients as FRONTLINE Plus but costs less.* SENTRY Fiproguard Plus contai...

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Natural Yard and Kennel Spray, 32 oz - Jeffers - Animal Health & Wellness > Flea & Tick Control
Natural Yard and Kennel Spray, 32 oz - Jeffers - Animal Health & Wellness > Flea & Tick Control
Sold out
$24.99
$24.99 - $24.99
$24.99
$22.99
$22.99 - $22.99
$22.99

Natural Yard and Kennel Spray, 32 oz

Natural Chemistry
Out of stock

Natural Chemistry Natural Yard and Kennel Spray Natural breakthrough product, kills fleas and ticks on contact. Hose end sprayer conveniently ho...

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DeFlea Concentrated Shampoo for Pets (Gallon) - Jeffers - Animal Health & Wellness > Flea & Tick Control
Sold out
$40.49
$40.49 - $40.49
$40.49
$37.49
$37.49 - $37.49
$37.49

DeFlea Concentrated Shampoo for Pets, Gallon

Natural Chemistry
Out of stock

DeFlea Concentrated Pet Shampoo for Fleas & Ticks DeFlea Concentrated Pet Shampoo contains Dioctyl Sodium Sulfosuccinate (a common food addi...

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Natural Flea and Tick Shampoo, 16.9 oz - Jeffers - Animal & Pet Supplies > Pet Grooming > Pet Shampoo & Conditioner
Natural Flea and Tick Shampoo, 16.9 oz - Jeffers - Animal & Pet Supplies > Pet Grooming > Pet Shampoo & Conditioner
Sold out
$7.99 - $7.99
$7.99
$9.49
$9.49 - $9.49
$9.49

Natural Flea and Tick Shampoo, 16.9 oz

Natural Chemistry
Out of stock

Natural Flea and Tick Shampoo, 16.9 oz Natural's Chemistry Natural Formula is composed of natural cinnamon oil, clove oil, and cedar wood oil wh...

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